| Study on the challenges and strategies of hydropower intelligent construction in high-altitude areas is of great significance to promote the safety, high-quality, efficiency and green construction. Firstly, the hydropower characteristics of environment, structures and construction in high-altitude areas are summarized in this paper, and the challenges of high-altitude intelligent construction are elucidated from the aspects of ecological priority, intrinsic safety, excellent quality, resource utilization and value creation. Based on the closed-loop control theory of "comprehensive perception, true analysis, real-time control, continuously optimize", focusing on the new problems that will arise in the construction of hydropower projects in high altitude areas, a three-dimensional, four element collaborative system analysis model of intelligent construction is established. Aiming at the ecology of typical river sections, the underground healthy environment, the effective use of excavation materials, the intelligent lining of long and large tunnels, the intelligent vibro-stone columns of deep overburden foundations, and the prevention of geo-disasters, the corresponding intelligent construction methods and countermeasures are proposed. The methods and countermeasures can give full play to the important role of digital and intelligent technology and management in the six management elements of resource input, technological process, business process, structural state, project progress and physical cost, and promote the technological innovation and management improvement of intelligent construction of high altitude hydropower projects. The study results are of guiding significance for the development of intelligent construction of hydropower projects in high altitude areas, and can also be used as reference for other similar projects and infrastructure engineering construction.